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To actually have an understanding of the overall performance of created-in foundation features, you’ll have to have to understand a bit about R’s C API. In R’s C interface, you’ll find out just a little about R’s C internals.
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The last 20 years have noticed an ever-increasing curiosity in The category of joint designs for longitudinal and time-to-occasion info. These models constitute an attractive paradigm for your Investigation of follow-up details that is mainly relevant in two configurations: Initially, when focus is over a survival end result and we would like to account for the effect of an endogenous time-dependent covariate measured with mistake, and 2nd, when aim is within the longitudinal outcome and we want to accurate for nonrandom dropout.
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The final detail to convey on The subject of successful Understanding pertains to the old (~2000 many years old!) declaring docendo discimus
Yet another useful part during the help file is See Also:. From the optim() help page, it backlinks to enhance() which can be much more appropriate for this use situation.
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